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If you've already used one of our molecules, please leave a review.
Our FAS in vivo tool compound BI 99179 is characterised by high potency, good selectivity and significant peripheral and central exposure upon oral administration in rats.
BI 665915 demonstrates nanomolar FLAP binding potency and is a molecule suitable for testing biological hypotheses in vitro and also in vivo.
BI 831266 is a potent and selective Aurora B inhibitor that inhibits cell proliferation and could be used as a tool compound for testing biological hypotheses.
BI 653048 is a “dissociated” GR agonist (displaying different transcriptional regulatory profiles between gene transrepression and transactivation) with selectivity for other nuclear receptors (MR, PR) and good drug-like properties.
CCR1 is a key chemokine receptor for human monocyte/macrophage chemotaxis. BI-639667 blocks influx of pro-inflammatory cells to the site of inflammation.