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If you've already used one of our molecules, please leave a review.
BI-1230 is a single digit nanomolar inhibitor of Hepatitis C Virus (HCV) NS3 protease activity and of viral replication. BI-1230 was shown to be highly selective against other serine/cysteine proteases and to be suitable for in vivo studies.
BI-1388 is a nanomolar to picomolar inhibitor of Hepatitis C Virus (HCV) NS3 protease activity and of viral replication for various HCV genotypes and for resistant mutants D168V and R155K.
BI-1950 potently inhibits the binding of LFA-1 to ICAM-1 with a KD value of 9 nM and the production of IL-2 in human PBMC and whole blood with an IC50 value of 3 nM and 120 nM, respectively.
BI-9627 is a highly potent NHE1 inhibitor with low DDI potential, excellent pharmacokinetics, and good selectivity against NHE2 and NHE3.
BI-2536 was the first potent and selective PLK1 inhibitor which entered clinical trials. It is a suitable in vitro and in vivo tool to study PLK function.
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