Get access to a unique dataset and detect novel methylation patterns in a large population cohort

01 July 2024

Technical advances in genome sequencing, including long read sequencing, became very popular in recent years allowing us to overcome technical challenges in linking disease phenotypes to nucleotide polymorphisms. For the first time, we are offering a collection of approximately 900 human samples from the 1,000 Genomes Project free of charge and sharing it with data scientists across the globe*. The data generated via Oxford Nanopore Technology (ONT) allow users to accurately detect DNA methylation and hydroxy-methylation patterns at scale, to address specific questions related to both types of DNA methylations, linking them to quantitative trait loci and pathological disease mechanisms.

To secure your chance to access this unique large population cohort dataset, we invite you to submit research proposals that address the following question:

How would you propose to improve our understanding of DNA methylation mechanisms and signature for target identification from the 1,000 Genomes Project cohort – using data analytics?

Boehringer Ingelheim will review all proposals and, upon its selection, based on key success criteria outlined as part of this call, provide a limited number of successful applications with access to this exclusive dataset for their independent research. Please note, as part of this call, no additional budgetary funding will be provided. All intellectual property generated from this call will be owned by the respective scientists.

Apply soon to get access to this dataset as your proposals can only be accepted if they arrive by September 19, 2024, 11:59 pm PST.

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About opnMe:

opnMe.com, the open innovation portal of Boehringer Ingelheim, aims to accelerate research initiatives to enable new insights of disease biology in areas of high unmet medical need by sharing well-characterized molecules and offer collaborations for science. In the spirit of collaboration, our molecules are provided to the scientific community to help unlock and fulfill their full potential. These molecules are either freely available as “Molecules to Order” or applied via scientific research submissions as “Molecules for Collaboration”. Interested scientists are invited to submit testable research hypotheses with these assets in novel diseases or combinations. With our “opn2EXPERTS” and “techMATCH” programs, we enlist scientific advice on key scientific issues to fuel further drug discovery and deliver novel solutions that benefit unmet patient needs. Our “opn2TALENTS” postdoc grants awards opportunities for high-level talents to pitch their scientific ideas and approaches for a well-defined research question, to conduct their research at one of our discovery research sites in Germany, Austria, or the US.