1 December 2025
We are offering an exceptional PostDoc grant to elucidate cellular and molecular mechanisms driving neuromuscular junction dysfunction in primary and secondary sarcopenia. This unique opportunity provides highly talented individuals the chance to pursue their own postdoctoral project proposal within the cutting-edge scientific environment of Boehringer Ingelheim's sarcopenia team in Biberach/Riss, Germany.
Sarcopenia, the progressive loss of muscle mass and function, significantly impacts mobility and quality of life, especially in aging populations and individuals with chronic conditions like diabetes and CKD. While much is known about muscle-intrinsic mechanisms, the neuromuscular junction (NMJ) has emerged as a critical yet underexplored site of dysfunction in sarcopenia. The molecular and cellular drivers of NMJ degeneration remain poorly understood, presenting a major gap in the quest for effective interventions. Advancing our understanding of NMJ biology could pave the way for novel therapeutic strategies to preserve neuromuscular integrity. Researchers are invited to address this urgent need by exploring NMJ degeneration mechanisms and identifying targets for early intervention. To join Boehringer Ingelheim and contribute to our sarcopenia research, we are inviting scientists to answer the following question:
How would you propose to elucidate cellular and molecular mechanisms driving neuromuscular junction dysfunction in primary and secondary sarcopenia using in vitro models?
Should your submission become accepted, you will work as part of an international team of highly skilled scientists focusing on sarcopenia and gain valuable insights into the drug discovery process in the pharmaceutical industry. Additionally, you will have the opportunity to receive expert mentoring, attend prestigious international conferences, and publish your research in high-impact journals.
Please submit your complete application package, including your project plan, CV, publication list, and letters of recommendation to become eligible for this call. All applications that arrive through January 22, 2026, 11:59 pm PST will receive a review of our scientific expert team.
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About our opn2TALENTS program:
Would you like to advance your research career as a PostDoc in the field of cellular and molecular biology at one of the leading pharmaceutical companies? Benefit from a fully funding position and access a fully resourced and state-of-the-art research environment? With defined scientific questions such as the one for this opn2TALENTS call, we provide a unique opportunity for high class talents to pitch their scientific ideas for a well-defined research question. The winner will have the opportunity to execute his/her postdoctoral research at Boehringer Ingelheim. The grant is for a duration of two years, with the possibility of a one-year extension.
About opnMe:
opnMe.com, the open innovation portal of Boehringer Ingelheim, fosters science and collaboration initiatives in areas of high unmet medical need. As part of our “Molecules to Order” pillar, we share well-characterized tool compounds free of charge with no IP strings attached. With our current “opn2EXPERTS” call on central brain pain mechanisms and “techMATCH” call on harnessing intracellular mechanisms, we enlist scientific advice on key biologic issues to fuel further drug discovery and deliver novel solutions that benefit unmet patient needs.