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17 March 2025

Glutamate is a vital central nervous system neurotransmitter that plays a role in various neuronal functions. The metabotropic glutamate receptors (mGluRs) regulate glutamate release and signaling pathways. Among these receptors, mGluR2, a receptor highly expressed in limbic regions throughout the brain, functions as an auto-receptor at pre-synaptic terminals.

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27 March 2025

The top three most ordered molecules on opnMe in 2024 have one thing in common. They all emerged from a research collaboration between the Centre of Targeted Protein Degradation (CeTPD) at the University of Dundee and Boehringer Ingelheim.

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10 February 2025

Read the full interview with Deepa Ghosh, Professor at the Institute of Nano Science and Technology in India, who talks about her experience with opnMe and the importance of open innovation in her work and how it is driving her research in osteoarthritis (OA).

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10 February 2025

The human ATP-binding cassette transporter subfamily C (ABCC) consists of 12 integral membrane proteins. Among them, nine proteins (ABCC1-ABCC6, ABCC10-ABCC12) form the multidrug resistance protein subfamily. These MRP proteins are widely expressed in the body. MRP4, for instance, is expressed in various tissues and organs, including the brain, liver, and kidney.

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18 December 2024

Don’t miss the chance to connect with other scientists and researchers in the life science community at Boehringer Ingelheim’s Transforming Science Day at the European Molecular Biology Laboratory (EMBL) campus in Heidelberg on February 25, 2025.

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