46
Molecules for free

04 March 2024

Orexins or hypocretins are two neuropeptides (OX-A and OX-B) that are synthesized in the hypothalamus, and serve as ligands for the G protein-coupled receptors OX1 and OX2. While the role of orexins was initially thought to be limited to the regulation of...

39
Molecules for free

19 February 2024

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system (CNS), exerting its effects via two classes of receptors, GABAA and GABAB. GABAA receptors (GABAARs) are ligand-gated ion channels typically...

17
Molecules for free

22 January 2024

GPR88 is a G-protein coupled receptor (GPCR) expressed primarily in the GABAergic medium spiny neurons of the striatum, and to a lesser extent in the cerebral cortex, amygdala, and hypothalamus. Although its exact function and endogenous ligands are...

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