General literature
New perspectives for better R&D performance: lessons learned from leading pharma companies

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Drug Discov Today 2026, 104677. Online ahead of print.

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Structural variation in 1,019 diverse humans based on long-read sequencing

Schloissnig S., Pani S., Ebler J., Hain C., Tsapalou V., Söylev A., Hüther P., Ashraf H., Prodanov T., Asparuhova M., Magalhães H., Höps W., Sotelo-Fonseca J. E., Fitzgerald T., Santana-Garcia W., Moreira-Pinhal R., Hunt S., Pérez-Llanos F. J., Wollenweber T. E., Sivalingam S., Wieczorek D., Cáceres M., Gilissen C., Birney E., Ding Z., Jensen J. N., Podduturi N., Stutzki J., Rodriguez-Martin B., Rausch T., Marschall T., Korbel J. O.

Nature. 2025, 644(8076):442-452.

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Complex I Modulator BI4500 Reduces MASH by Limiting Oxidative Stress and Reprogramming Lipid Metabolism via AMPK in MCD Rats

Di Pasqua L. G., Lotti S., Trucchi M., Palladini G., Croce A. C., Protopapa F., Feletti F., Kauschke S. G., Sun P., Vairetti M., Ferrigno A.

Antioxidants (Basel). 2026, 15(1):82.

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Mapping the functional connectome of the claustrum: Noise filtering via local inhibitory circuits

Graf M., Sadeh S., Augustine G. J.

Cell Rep. 2026, 45(1):116821.

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Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation

Rutkowski M. R., Stephen T. L., Svoronos N., Allegrezza M. J., Tesone A. J., Perales-Puchalt A., Brencicova E., Escovar-Fadul X., Nguyen J. M., Cadungog M. G., Zhang R., Salatino M., Tchou J., Rabinovich G. A., Conejo-Garcia J. R.

Cancer Cell. 2015, 27(1):27-40.

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TLR5 Signaling Causes Dendritic Cell Dysfunction and Orchestrates Failure of Immune Checkpoint Therapy against Ovarian Cancer

McGinty M. T., Putelo A. M., Kolli S. H., Feng T-Y., Dietl M. R., Hatzinger C. N., Bajgai S., Poblete M. K., Azar F. N., Mohammad A., Kumar P., Rutkowski M. R.

Cancer Immunol Res. 2025, 13(5):696-711.

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