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18 March 2024

Fibrosis is a pathological feature of many human inflammatory diseases such as pulmonary fibrosis, Crohn’s disease, scleroderma, metabolic-associated steatohepatitis, chronic kidney diseases as well as cancer. Complex multi-dimensional...

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05 February 2024

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease with a high mortality rate, characterized by scarring of the lungs, which reduces their capacity to transfer oxygen to the bloodstream. Therapeutic options are limited since the...

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8 January 2024

Novel treatment approaches such as peptides demonstrate marked improvements for patients. However, their poor oral bioavailability requires subcutaneous injections, leading to a high ecological burden due to single-use devices and frequent injections.

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05 June 2023

In the first edition of our new opnMe series, Katherine Donovan introduces the Degradation Proteomics Initiative (DPI) that she has established within Eric Fischer’s lab to provide an independent quality assessment of publicly available molecular...

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20 January 2023

Watch the recording of our opnMe online seminar from Nov 29, 2022, and follow the journey of the PROTAC ACBI1, a cooperative degrader of BAF subunits SMARCA2 and 4, which are essential parts of the chromatin remodeler BAF (SWI/SNF) complex.

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Hear from our collaborators

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