16
Molecules for free

9 October 2025

opnMe now offers 100 well-characterized preclinical molecules for free to researchers worldwide. Since 2017, the program has supported over 10,000 orders from 54 countries, contributing to more than 240 scientific publications and advancing research across various fields. Explore the full collection of molecules today.

5
Molecules for free

6 October 2025

Vanin 1 and vanin 2 regulate cellular redox homeostasis and play key roles in maintaining oxidative balance and modulating inflammation. To advance further exploration, we offer BI-4122, a dual vanin 1/2 inhibitor. BI-4122 is optimized for intravenous and oral administration and comes along with BI-9534, an inactive control, to enable robust experimental designs.

29
Discover us

6 October 2025

Watch our online seminar to discover how sharing a selective inhibitor via opnMe advanced SOS1-RAS research in novel disease indications. Hear how two academic researchers uncovered novel therapeutic strategies in oncology and diabetes, powered by open science and BI-3406.

15
Discover us

18 September 2025

opnMe now offers selectivity data for a subset of initial twelve molecules, in addition to the data already available—all free to access. Researchers can now explore enhanced selectivity profiles generated using the PRESTO-TANGO screen from the Psychoactive Drug Screening Program (PDSP), supporting deeper insights into GPCR interactions.

5
Molecules for free

8 September 2025

Positive allosteric modulators of mGluR1 restore cortical inhibitory tone and improve cognitive performance in models of NMDA receptor hypofunction. To support ongoing research into mGluR1 function, we now offer two highly selective positive allosteric modulators of mGluR1: BI02982816 and its chemically optimized reiteration, BI-1752.

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