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Collaborate with us

9 January 2026

We now share a well-characterized small molecule inhibitor of ALPK1, BI-4286, to dissect the molecular mechanisms underlaying ALPK1 signaling in disease pathology. The focus is on select indications outside of ROSAH syndrome and infectious diseases. Submit your research proposal for a chance to access BI-4286 and receive funding.

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PostDoc Grants

1 December 2025

We are offering an exceptional PostDoc grant to elucidate cellular and molecular mechanisms driving neuromuscular junction dysfunction in primary and secondary sarcopenia. This unique opportunity provides highly talented individuals the chance to pursue their own postdoctoral project proposal within the cutting-edge scientific environment of Boehringer Ingelheim in Biberach/Riss, Germany.

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Collaborate with us

1 December 2025

Nociplastic pain, a subtype of chronic pain, arises from altered nociception in the absence of clear tissue damage. Its poorly understood pathogenesis and the limited efficacy of current treatments underscore the urgent need for identifying and validating innovative pharmacological approaches that target central neurobiological pathways involved in pain processing.

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Molecules for free

25 November 2025

By regulating intracellular cGMP levels, phosphodiesterase-9 (PDE9) plays a critical role in neuronal signaling, vascular function, and cell survival. By making our potent, selective, and brain-penetrant PDE9 inhibitor, BI 409306 (osoresonontrine) available to scientists free of charge, we incentivize new research to fully understand the role of the molecule in the context of disease.

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Collaborate with us

17 November 2025

A large portion of the proteome remains “undruggable” with traditional small molecules and biologics. To expand the druggable target landscape in areas of high unmet medical needs, novel innovative approaches could focus on targeting intracellular mechanisms, such as influencing nuclear translocation, organelle routing, molecular condensates, and spatial-temporal control mechanisms.

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