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If you've already used one of our molecules, please leave a review.
BI-3614 is a highly selective, equipotent orthosteric inhibitor of QPCT and QPCTL and thus qualifies as an in vitro tool compound suitable for cell-based studies.
BI-4500 is a potent and selective NADH:ubiquinone oxidoreductase (Complex I) reactive oxygen species (ROS) modulator. BI-5330 is available as negative control.
BI 7828 is a highly potent oral MDM2–p53 antagonist molecule with favorable PK, prolonged exposure, and intermittent dosing potential.
ACBI4 is a first-in-class KRAS degrader and VHL-recruiting PROTAC that targets multiple oncogenic KRAS variants in vitro.
BI‑3757 is a cereblon (CRBN) binder that stabilizes CRBN in its open conformation. BI‑4506 is a structurally similar analog that does not bind CRBN and is available as a negative control.
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