2
PostDoc Grants

1 December 2025

We are offering an exceptional PostDoc grant to elucidate cellular and molecular mechanisms driving neuromuscular junction dysfunction in primary and secondary sarcopenia. This unique opportunity provides highly talented individuals the chance to pursue their own postdoctoral project proposal within the cutting-edge scientific environment of Boehringer Ingelheim in Biberach/Riss, Germany.

2
Molecules for free

25 November 2025

By regulating intracellular cGMP levels, phosphodiesterase-9 (PDE9) plays a critical role in neuronal signaling, vascular function, and cell survival. By making our potent, selective, and brain-penetrant PDE9 inhibitor, BI 409306 (osoresonontrine) available to scientists free of charge, we incentivize new research to fully understand the role of the molecule in the context of disease.

36
Molecules for free

9 October 2025

opnMe now offers 100 well-characterized preclinical molecules for free to researchers worldwide. Since 2017, the program has supported over 10,000 orders from 54 countries, contributing to more than 240 scientific publications and advancing research across various fields. Explore the full collection of molecules today.

10
Molecules for free

6 October 2025

Vanin 1 and vanin 2 regulate cellular redox homeostasis and play key roles in maintaining oxidative balance and modulating inflammation. To advance further exploration, we offer BI-4122, a dual vanin 1/2 inhibitor. BI-4122 is optimized for intravenous and oral administration and comes along with BI-9534, an inactive control, to enable robust experimental designs.

5
Molecules for free

8 September 2025

Positive allosteric modulators of mGluR1 restore cortical inhibitory tone and improve cognitive performance in models of NMDA receptor hypofunction. To support ongoing research into mGluR1 function, we now offer two highly selective positive allosteric modulators of mGluR1: BI02982816 and its chemically optimized reiteration, BI-1752.

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