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5 November 2024

We recently had the chance to speak to Laura-Marie Zimmermann, a former postdoctoral researcher at the University Hospital Cologne, about her experience with opnMe and her interaction with scientists from Boehringer Ingelheim.

46
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28 October 2024

Christian Wolfrum, VP of Research and Professor at the Department of Health Sciences and Technology at ETH Zurich, shared his collaboration experience with Boehringer Ingelheim, enabled through an opn2EXPERTS question on opnMe.

72
Molecules for free

30 September 2024

The Kirsten rat sarcoma viral oncogene homologue (KRAS) is the most mutated oncogene in human cancers. Through opnMe, we offer ACBI3, a first-in-class proteolysis targeting chimera (VHL PROTAC) which arises from a successful collaboration with...

62
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29 July 2024

Excessive fructose consumption is associated with metabolic disorders such as obesity, diabetes and non-alcoholic fatty liver disease (NAFLD). Ketohexokinase (KHK) is an enzyme catalyzing the first committed step in fructose metabolism, by...

69
Molecules for free

15 July 2024

The enzyme GTP cyclohydrolase I (GCH1) catalyzes the first and rate limiting step in the biosynthesis of tetrahydrobiopterin (BH4) from GTP. BH4 is a critical cofactor in the degradation of the amino acid phenylalanine, the production of the signaling molecule nitric oxide (NO), as well as the synthesis of the neurotransmitters...

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